Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan
Photo by Linda Cronan

Popular places to visit

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.

USAA Corporate Office Headquarters

South Texas Medical Center

If South Texas Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

South Texas Medical Center

University of Texas Health and Science Center at San Antonio

If University of Texas Health and Science Center at San Antonio is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

University of Texas Health and Science Center at San Antonio

CHRISTUS Santa Rosa Hospital - Medical Center

If CHRISTUS Santa Rosa Hospital - Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

CHRISTUS Santa Rosa Hospital - Medical Center

University Hospital - University Health System

If University Hospital - University Health System is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

University Hospital - University Health System

Methodist Healthcare

If Methodist Healthcare is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.

Methodist Healthcare

Things to do

San Antonio: Discovery Tour at Natural Bridge Caverns

San Antonio: Discovery Tour at Natural Bridge Caverns

Rp605.628
per adult
90% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
San Antonio: San Antonio Zoo Any Day Ticket

San Antonio: San Antonio Zoo Any Day Ticket

Rp655.929
per adult
96% of travellers recommend
San Antonio: San Antonio Zoo Any Day Ticket
Best of San Antonio Tour

Best of San Antonio Tour

Rp2.758.972
per adult
94% of travellers recommend
Best of San Antonio Tour
Enchanting San Antonio: A Romantic Journey

Enchanting San Antonio: A Romantic Journey

Rp10.280.541
per adult
Enchanting San Antonio: A Romantic Journey
Hop on Board the Ghost Bus

The Haunted Ghost Bus Tour in San Antonio

Rp923.780
per adult
96% of travellers recommend
The Haunted Ghost Bus Tour in San Antonio
Scenic San Antonio Night Tour

Scenic San Antonio Night Tour

Rp2.001.937
per adult
86% of travellers recommend
Scenic San Antonio Night Tour
See all activities in San Antonio

Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is Rp1.461.211 per night from 27 Apr to 28 Apr
Rp1.461.211
Rp1.727.282 total
includes taxes & fees
27 Apr - 28 Apr
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,406 reviews)
"The stay was nice got some rest from a long drive from Mexico I liked it was super nice in the lobby and front desk was very friendly and very clean rooms"

Reviewed on 17 Apr 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is Rp1.876.722 per night from 19 May to 20 May
Rp1.876.722
Rp2.230.099 total
includes taxes & fees
19 May - 20 May
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,001 reviews)
"Great ambiance with all amenities"

Reviewed on 10 Apr 2025

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
The price is Rp1.687.531 per night from 27 Apr to 28 Apr
Rp1.687.531
Rp1.994.693 total
includes taxes & fees
27 Apr - 28 Apr
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,213 reviews)
"The hotel is nice. The personnel is also very nice. However, it was extremely noisy during the night. It apoears that some cleaning and maintenence around the room was being done. We were not able to rest."

Reviewed on 16 Apr 2025

Drury Inn & Suites San Antonio Northwest Medical Center
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is Rp1.471.674 per night from 19 May to 20 May
Rp1.471.674
Rp1.739.650 total
includes taxes & fees
19 May - 20 May
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the ...
8/10 Very Good! (4,848 reviews)
"Didnt like the $50 a day valet with no clear option to park your car at this location"

Reviewed on 19 Apr 2025

Riverwalk Plaza
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3 out of 5
303 Blum Street, San Antonio, TX
The price is Rp1.201.642 per night from 21 Apr to 22 Apr
Rp1.201.642
Rp1.740.029 total
includes taxes & fees
21 Apr - 22 Apr
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (3,550 reviews)
"The hotel was nice..... the young lad signing us in had absolutely no idea what to do and kept yawning which is rarely a good sign. I asked if we were keepig him up he yawned so many times. Room was good but for our last night and morning of check out we had no hot water. I rang reception at 9pm ..."

Reviewed on 17 Apr 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Crockett Hotel
Crockett Hotel
3 out of 5
320 Bonham, San Antonio, TX
The price is Rp1.767.359 per night from 19 May to 20 May
Rp1.767.359
Rp2.089.178 total
includes taxes & fees
19 May - 20 May
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,366 reviews)
"Excellent"

Reviewed on 18 Apr 2025

Crockett Hotel
See all 4,280 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like San Antonio Zoo and Aquarium and San Antonio River.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill
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Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

Uptown

Medical Center District Travel Guide