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Check prices for these dates

Tonight
19 Apr - 20 Apr
Tomorrow
20 Apr - 21 Apr
Next weekend
25 Apr - 27 Apr
In two weeks
2 May - 4 May

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Top Trending Hotels Near South Main, Houston

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (837)
"This was the first time in many visits that we were puzzled about the breakfast selections. We were told that serving begins at 6 and we came down at 6:30. They did not have any hot items out. Shortly after they brought out some scrambled eggs and sausage gravy. No kind of meat was offered and no explanation as to why. Nice place all in all. "
The price is Rp1.525.850
Rp1.785.243 total
includes taxes & fees
2 May - 3 May
Comfort Suites near Texas Medical Center - NRG Stadium
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.6 out of 10, Good, (751)
"Very nice"
The price is Rp1.350.160
Rp1.579.688 total
includes taxes & fees
24 Apr - 25 Apr
Candlewood Suites Houston Medical Center by IHG
Quality Inn & Suites NRG Park - Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1000)
"The staff was absolutely amazing in the breakfast even better. Haven’t had a continental breakfast like that in a while.😎"
The price is Rp989.836
Rp1.158.108 total
includes taxes & fees
19 May - 20 May
Quality Inn & Suites NRG Park - Medical Center
Wyndham Houston near NRG Park/Medical Center
View from property

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1024)
"."
The price is Rp2.345.903
Rp2.744.706 total
includes taxes & fees
20 Apr - 21 Apr
Wyndham Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical Center
Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (867)
"The property was quiet and secure. There is a lot of maintenance and upgrading of the facilities happening right now. Overall it is a good value."
The price is Rp2.008.363
Rp2.349.785 total
includes taxes & fees
27 Apr - 28 Apr
Wingate Houston near NRG Park/Medical Center
Americas Best Value Inn NRG Park Medical Center
Desk, iron/ironing board, free WiFi, bed sheets

Americas Best Value Inn NRG Park Medical Center

2.0 star property
7.6 out of 10, Good, (700)
"Breakfasts "
The price is Rp1.219.363
Rp1.426.654 total
includes taxes & fees
21 Apr - 22 Apr
Americas Best Value Inn NRG Park Medical Center
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1566)
"I would absolutely recommend this place due to the convenience of this place as well as the cleanliness and staff. They were amazing to say the least "
The price is Rp1.873.347
Rp2.203.434 total
includes taxes & fees
1 May - 2 May
Hyatt Place Houston Medical Center
Hyatt House Houston Medical Center
Lobby

Hyatt House Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (946)
"Really enjoyed as a cancer patient attending MD Anderson Cancer Center that they offer a complimentary shuttle to any locations within a 2 mile radius (which includes the center's various buildings), however on the last day of my stay, "
The price is Rp2.278.395
Rp2.679.848 total
includes taxes & fees
26 Apr - 27 Apr
Hyatt House Houston Medical Center
Blossom Hotel Houston
City view

Blossom Hotel Houston

4.0 star property
9.2 out of 10, Wonderful, (3242)
"An amazing experience staff was so great. I cannot wait to go back. Cleanliness was perfectionist. Staff was very helpful, kind and caring and just made me feel so much at home even though I was far away from home anytime I go to Houston. This will definitely be the spot I stay at."
The price is Rp2.582.181
Rp3.021.153 total
includes taxes & fees
20 Apr - 21 Apr
Blossom Hotel Houston
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1003)
"Very clean "
The price is Rp1.351.679
Rp1.586.438 total
includes taxes & fees
21 Apr - 22 Apr
Extended Stay America Suites Houston Med Ctr Braeswood Bl
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lobby

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very good, (309)
"I loved how walkable it was to MD Anderson and various shopping and eating options. Excellent staff. "
The price is Rp2.137.472
Rp2.500.844 total
includes taxes & fees
18 May - 19 May
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1005)
"Best economy hotel in the area. "
The price is Rp1.420.200
Rp1.661.634 total
includes taxes & fees
26 Apr - 27 Apr
Americas Best Value Inn Medical Center Downtown
Extended Stay America Suites Houston Med Ctr Greenway Plaza
Studio, 2 Double Beds, Non Smoking | Desk, iron/ironing board, free WiFi

Extended Stay America Suites Houston Med Ctr Greenway Plaza

2.5 star property
6.8 out of 10, (1002)
"The A/C was cold, the bed was comfortable, the room was clean, and the staff was pleasant and helpful."
The price is Rp1.105.825
Rp1.293.693 total
includes taxes & fees
22 Apr - 23 Apr
Extended Stay America Suites Houston Med Ctr Greenway Plaza
WoodSpring Suites Houston 288 South Medical Center
Fridge, microwave, stovetop, dishwasher

WoodSpring Suites Houston 288 South Medical Center

2.5 star property
7.4 out of 10, Good, (359)
"Front desk closes at 9pm you have to call to get in the building "
The price is Rp1.113.713
Rp1.303.044 total
includes taxes & fees
20 Apr - 21 Apr
WoodSpring Suites Houston 288 South Medical Center
Home2 Suites by Hilton at the Galleria
View from room

Home2 Suites by Hilton at the Galleria

3.0 star property
8.8 out of 10, Excellent, (760)
"I arrived into town with special circumstances "
The price is Rp2.008.363
Rp2.349.783 total
includes taxes & fees
1 May - 2 May
Home2 Suites by Hilton at the Galleria
Sonesta ES Suites Houston Galleria
Lobby

Sonesta ES Suites Houston Galleria

3.0 star property
8.2 out of 10, Very good, (1004)
"The property had a homelike feeling to it. It was comfortable and spacious. The property is starting to show its age a little by the wear and tear signs on furniture and corners of doors, etc. Nevertheless, I would stay there again."
The price is Rp1.839.593
Rp2.152.324 total
includes taxes & fees
27 Apr - 28 Apr
Sonesta ES Suites Houston Galleria
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
8.8 out of 10, Excellent, (1004)
"Great hotel"
The price is Rp2.119.076
Rp2.498.895 total
includes taxes & fees
11 May - 12 May
Hyatt Regency Houston/Galleria
Hyatt Place Houston/Galleria
Lobby

Hyatt Place Houston/Galleria

3.0 star property
8.6 out of 10, Excellent, (1004)
"I was in room 421 it is a very nice room the hotel very practical, clean and the staff very friendly…when checking out I for got two boxes am sure that I will find them when I will ask them to send them back to me to DC"
The price is Rp1.873.347
Rp2.202.956 total
includes taxes & fees
27 Apr - 28 Apr
Hyatt Place Houston/Galleria
The Chifley Houston, Tapestry Collection by Hilton
Lobby

The Chifley Houston, Tapestry Collection by Hilton

4.0 star property
9.0 out of 10, Wonderful, (1007)
"The Chifley staff were responsive and friendly. Overall, we had a pleasant stay. "
The price is Rp2.567.836
Rp3.004.368 total
includes taxes & fees
25 Apr - 26 Apr
The Chifley Houston, Tapestry Collection by Hilton
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.2 out of 10, Very good, (1008)
"Loved it really nice, staff was nice and welcoming , the only issue was the plumbing, the toilet flushed very slowly and we had to hold the handle down, and housekeeping never came to clean, and very slow with receiving towels, and ice machine on 16th floor didn’t work we have to go to anther floor or staff brought a bucket of ice to us, Overall very nice hotel and I would stay again."
The price is Rp2.718.885
Rp3.615.509 total
includes taxes & fees
17 May - 18 May
The Royal Sonesta Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 65 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.