Photo by Hazem Abdul

Search Hotels in South Main, Houston

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near South Main, Houston

The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.4 out of 10, Very good, (1163)
"Nice"
The price is Rp2.306.876
Rp2.699.045 total
includes taxes & fees
9 Jan - 10 Jan
The Whitehall Houston
Holiday Inn Houston Downtown, an IHG Hotel
Property amenity

Holiday Inn Houston Downtown, an IHG Hotel

3.0 star property
8.6 out of 10, Excellent, (1008)
"Perfect location and perfect accommodations with friendly staff and nicely kept rooms. Will stay here again and I do recommend! "
The price is Rp1.220.386
Rp1.710.960 total
includes taxes & fees
26 Jan - 27 Jan
Holiday Inn Houston Downtown, an IHG Hotel
Blossom Hotel Houston
City view

Blossom Hotel Houston

4.0 star property
9.2 out of 10, Wonderful, (3015)
"We loved this hotel and planned on staying here next time we are in Houston. My husband has a medical procedure coming up soon at the Medical Center and if we have to stay overnight, it will be here. The hotel and staff exceeded my expectations tremendously.!"
The price is Rp2.106.550
Rp2.464.662 total
includes taxes & fees
26 Jan - 27 Jan
Blossom Hotel Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.0 out of 10, Very good, (1664)
"Safe, quiet, shopping, transportation easy access."
The price is Rp1.971.621
Rp2.322.832 total
includes taxes & fees
1 Feb - 2 Feb
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston
Exterior

Club Quarters Hotel Downtown, Houston

4.0 star property
8.2 out of 10, Very good, (3090)
"Clean and friendly staff"
The price is Rp1.793.878
Rp2.098.837 total
includes taxes & fees
9 Jan - 10 Jan
Club Quarters Hotel Downtown, Houston
Marriott Marquis Houston
2 outdoor pools, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)

Marriott Marquis Houston

4.0 star property
8.8 out of 10, Excellent, (1009)
"Such an amazing pool deck. Wish they were heated in winter. 2 hot chocolates were $26, crazy. "
The price is Rp4.972.786
Rp6.390.111 total
includes taxes & fees
1 Feb - 2 Feb
Marriott Marquis Houston
Hilton Americas-Houston
Exterior

Hilton Americas-Houston

4.0 star property
9.2 out of 10, Wonderful, (1185)
"This was a beautiful hotel! Staff was friendly and helpful! "
The price is Rp3.277.216
Rp3.872.092 total
includes taxes & fees
9 Jan - 10 Jan
Hilton Americas-Houston
C. Baldwin, Curio Collection by Hilton
Outdoor banquet area

C. Baldwin, Curio Collection by Hilton

4.0 star property
8.4 out of 10, Very good, (967)
"I had a great stay . The staff was polite and very accommodating. The shuttle was perfect for our nearby activities . I would highly recommend "
The price is Rp2.598.159
Rp3.469.101 total
includes taxes & fees
25 Jan - 26 Jan
C. Baldwin, Curio Collection by Hilton
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.0 out of 10, Wonderful, (1287)
"I really enjoyed staying here. Comfy beds, good showers, great pool and hot tub, nice gym, free laundry. Breakfast was good too except when they ran out of coffee and took 30 min to replenish. Close enough to the museum district to walk or take the train that is close by. Big thumbs up to Alesia at the front desk when we checked in after a long travel day. Big thumbs down to Adam in the kitchen for mouthing off to me and then badmouthing me to other clients. "
The price is Rp1.776.111
Rp2.089.062 total
includes taxes & fees
5 Jan - 6 Jan
Hyatt Place Houston Medical Center
Hyatt Place Houston Downtown
Lobby sitting area

Hyatt Place Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (1416)
"Clean and spacious room however bed was not comfortable. It was not a big deal since we only stayed 1 night. We booked to stay close to the POST to see the NYE fireworks. It was nice walking around main street and we did walk back and forth to POST twice. The bartender working on NYE on the 16th floor was great!"
The price is Rp2.409.452
Rp2.860.525 total
includes taxes & fees
6 Jan - 7 Jan
Hyatt Place Houston Downtown
Hyatt Regency Houston Downtown
City view

Hyatt Regency Houston Downtown

4.0 star property
9.2 out of 10, Wonderful, (1002)
"While I was in the middle of the shower the water cut off completely. Called the front desk she told me the hotel was working on the water. The water was back on in about 20 minutes or so"
The price is Rp3.547.362
Rp4.250.031 total
includes taxes & fees
10 Jan - 11 Jan
Hyatt Regency Houston Downtown
Hilton Houston Plaza/Medical Center
Sun deck

Hilton Houston Plaza/Medical Center

3.5 star property
8.4 out of 10, Very good, (1117)
"The room smelled as if smokers had been there. Basic essentials such as drinking glass was not there Loading and offloading of baggage needs improvement. No one at the doors etc to assist or ask questions. Figure it out on your own."
The price is Rp1.389.464
Rp1.644.465 total
includes taxes & fees
26 Jan - 27 Jan
Hilton Houston Plaza/Medical Center
Cambria Hotel Houston Downtown Convention Center
Lobby

Cambria Hotel Houston Downtown Convention Center

3.0 star property
8.8 out of 10, Excellent, (1429)
"I was there for an overnight staycation. Everything was excellent. Property was clean, staff was exceptional. Will definitely return."
The price is Rp1.913.794
Rp2.239.139 total
includes taxes & fees
2 Feb - 3 Feb
Cambria Hotel Houston Downtown Convention Center
Rusk House Serviced Apartments
Check-in/check-out kiosk

Rusk House Serviced Apartments

4.5 star property
9.2 out of 10, Wonderful, (107)
"Love the room very comfortable everything you need is there. "
The price is Rp2.186.730
Rp2.558.474 total
includes taxes & fees
5 Jan - 6 Jan
Rusk House Serviced Apartments
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.2 out of 10, Very good, (1005)
"Bathroom outdated"
The price is Rp2.434.559
Rp3.265.370 total
includes taxes & fees
25 Jan - 26 Jan
The Royal Sonesta Houston Galleria
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
8.8 out of 10, Excellent, (1011)
"We came for the NYE on December 31, 2024. The hotel was a great pleasant surprise: easy valet parking, fast check-in, incredible staff, super clean, elegant and beautifully decorated! It is right next to The Galleria mall, 3 minutes walk. It has a great coffee shop in the lobby, as well as a bar. Elevators access with room key for safety. Everything was perfect, my wife and I fully recommend this jewel! "
The price is Rp2.340.287
Rp2.756.924 total
includes taxes & fees
4 Jan - 5 Jan
Hyatt Regency Houston/Galleria
The Post Oak Hotel at Uptown Houston
Outdoor pool, pool cabanas (surcharge), pool umbrellas

The Post Oak Hotel at Uptown Houston

5.0 star property
9.6 out of 10, Exceptional, (683)
"Stayed at The Post Oak Hotel over Christmas and had a fantastic stay. The room was wonderful and the staff fantastic. I would stay here again for sure! "
The price is Rp9.292.032
Rp10.871.678 total
includes taxes & fees
23 Jan - 24 Jan
The Post Oak Hotel at Uptown Houston
Moxy Houston Downtown
Front of property – evening/night

Moxy Houston Downtown

3.0 star property
9.0 out of 10, Wonderful, (308)
"Really nice hidden gem, treated me like a king I am will definitely be back 💪"
The price is Rp1.905.996
Rp2.262.280 total
includes taxes & fees
26 Jan - 27 Jan
Moxy Houston Downtown
Le Meridien Houston Downtown
Rooftop terrace

Le Meridien Houston Downtown

4.0 star property
8.6 out of 10, Excellent, (885)
"Room was clean and staff was friendly metro around the corner no problems. Only thing the pillows were super soft you lost the pillows at night like sleeping into the bed. "
The price is Rp2.578.722
Rp3.017.105 total
includes taxes & fees
10 Jan - 11 Jan
Le Meridien Houston Downtown
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Outdoor pool

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (1006)
"Its all good"
The price is Rp2.306.876
Rp2.734.535 total
includes taxes & fees
9 Jan - 10 Jan
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in South Main
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center, an IHG Hotel and Wyndham Houston near NRG Park/Medical Center.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 66 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.